Jalen Hurts is out for Week 6, and the Eagles’ response goes beyond simply handing the offense to Tanner McKee.

Hurts was ruled out against the Carolina Panthers with a blood clot in his calf, the latest turn in an injury that began in the Week 4 loss to the Los Angeles Rams. He played through it in Week 5 against the Jacksonville Jaguars, but the Eagles now have to move forward without him — and with a quarterback room that looks different than it did a week ago.

McKee will start in Hurts’ place, making his third career start and his first that doesn’t come in a Week 18 game. The Eagles also signed Joe Milton, who will sit behind McKee and Cole Payton as the third-string quarterback for Week 6.

That shuffle matters because it changes the way the rest of the offense gets evaluated.

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Darius Cooper is one of the clearest examples. The receiver has caught seven passes for 130 yards and four touchdowns over five games, and he leads the team in touchdown catches. He also has a relationship with McKee that dates back to the last two preseasons, a connection that could matter now that the Eagles are asking McKee to run the offense in a real game rather than a late-season placeholder role.

Cooper has already shown he can be a useful target in this offense. One of his catches went for 62 yards and a touchdown, and with Hurts unavailable, the Eagles may have to lean more heavily on him.

The timing of the quarterback change also gives the Eagles a chance to see what else they have around the position. Milton’s arrival came after Hurts was ruled out, and the team’s decision to add him reflects how quickly the depth chart had to be adjusted once Hurts was unavailable. At the same time, the Eagles are dealing with other injuries, including running back Will Shipley going on injured reserve after a foot injury in the Week 5 loss to the Jaguars.

That leaves Week 6 as more than a survival game at quarterback. McKee gets the start, Milton joins the room, and players like Cooper get a chance to show whether they can carry more of the load when the offense is built around a different passer.

For the Eagles, the question isn’t only whether McKee can keep the offense moving. It’s whether the injury-driven reset reveals a player or two who can matter once the quarterback situation settles.